Hereditary conditions and CON donors
What does it mean if a donor has a condition?
In a fast-developing world with new technologies and increased genetic screening, Cryos is being transparent about the fact that some of our donors have genetic conditions. Genetic conditions, also commonly referred to as hereditary conditions, are present in the general population and thus also in a selection of our donors.
If we receive information about a possible hereditary condition in a donor or a donor child, the information will be assessed. If there is a possibility that it is related to the donor, the information is made available on our website. A registered condition does not mean that the donor cannot be used, for more information please see the section: Who can use a CON donor?
Who can use a CON donor?
Danish authorities have instructed us that donors who have been registered with a genetic condition, can only be used if the recipient has already conceived a child with the donor. This counts for all countries including Denmark.
However, these donors would under certain circumstances still be applicable as long as there is transparency with respect to the detected condition.
It is a fact that all individuals, and, hence, also all donors and recipients are carriers of several mutations associated with hereditary diseases including diseases with recessive and multifactorial inheritance. Therefore, it is not possible to eliminate this risk, meaning that it can be misleading to withdraw donors with registered conditions because recipients might believe that the donors, who can be purchased, cannot be associated to hereditary diseases. This is not the case, as we know that all people are carriers of hereditary diseases, we just do not know the type of disease. This leads to the question, if you want to have this knowledge at all?
For donors with registered conditions, it applies that we have gained knowledge of a specific condition and subsequently if possible a risk assessment has been established concerning the specific condition, when using the donor.
For a number of cases where it has been possible to identify the exact mutation in a specific gene causing a recessive disease, it is possible to eliminate the risk of using the donor, by testing the recipient for mutations in the specific disease gene. For other types of inheritance, information on the severity of the specific condition together with the risk assessment provides the recipient with the information to decide whether the recipient still wants to use the given donor.
To conclude, if you want to buy sperm from a donor with a registered condition, you must declare that you already have a child with this donor and you must declare that you have received and understood the information concerning the registered condition.
Furthermore, we recommend that you seek local genetic counselling regarding questions about using a donor with a registered condition.
How do I report a suspected condition in a donor?
To report a suspected condition simply send us an e-mail or call our Customer Service.